Look for the truth in asthma

with the help of allergen specific IgE blood testing

Brought to you by Brought to you by Thermo Fisher

Your patient's most obvious allergen may only be part of their problem

Each allergen adds to the trigger load until the load is so great that despite their preventative medication, they experience asthma symptoms that require absence from school, require oral steroids or even emergency care in hospital.

Uncovering the true picture of allergic triggers is important when planning the best management for your patient.

Up to 80%
of allergic patients are sensitised to at least 3 allergens1,2
Exposure reduction is irrefutably proven to work 3,4,7,10
Allergens and viruses act together to exacerbate asthma9,10

The combination of viral infection and exposure to aeroallergens in sensitised children with asthma increases the risk of hospital admission almost 20-fold despite ICS use.10

Reducing allergen exposure, in children with asthma, reduces the risk of a virally induced exacerbation leading to hospital admission by nearly 50%.

Additionally (in sensitised children) allergen exposure reduction to all confirmed sensitisations can:7,10

Reduce medication use

Reduce symptom days

Reduce time off school

Allergen exposure reduction significantly reduces the risk of hospital admission in children with asthma
Risk of hospital admission (OR)
& Exposure
& Virus
Exposure & Virus
46% risk
Adapted from Murray CS, et al. 2006.10
Adapted from Murray CS, et al. 2006.10
*Prospective 12 month study of children aged 3-17 years with asthma. N=252 (84 children admitted to hospital with an acute asthma exacerbation; Control group 1: 84 children with stable asthma who were not admitted to hospital or require oral steroid for asthma exacerbation in the previous 12 months; Control group 2: 84 patients admitted to hospital with non-respiratory conditions. All controls were age and sex matched.
The combination of sensitisation, exposure, and viral infection was significantly associated with risk of hospital admission (p<0.001; OR19.4 (95%CI 3.7-101.5) following a multivariate analysis adjusting for the use of inhaled corticosteroids and duration of asthma symptoms.

Identifying and reducing allergen exposure can reduce asthma medication and reduce costs3,8,12

Initial specific IgE blood testing of children with respiratory and/or skin problems can reduce medication use over 2 years8...







Reducing exposure to all confirmed allergies in asthma can lead to:7

4  fewer missed school days

21  fewer symptom days

per year per patient
Specific IgE blood testing could help your patient take control of their asthma
A step-by-step guide to using specific IgE as a management strategy in asthma

We hope this guide will be helpful for you in finding those allergic triggers and employing strategies to alleviate symptoms in your patients.

Further information can be found at allergyai.com

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  1. Ciprandi G, et al. Eur Ann Allergy Clin Immunol 2008;40:77-83.
  2. Petersson CJ, et al. Sensitization profile in undiagnosed children with skin and respiratory allergy-like symptoms in primary care. Abstract presented at WAO, Buenos Aires, Argentina 6-10 December 2009.
  3. Eggleston PA. lmmunol Allergy Clin North Am 2003;23(3):533-547.
  4. 4. Wickman M. When allergies complicate allergies. Allergy. 2005;60 (Suppl 79):14'18.
  5. Gore RB, Custovic A, 2002, Aeroallergen avoidance: What practical advice can we give to patients? CPD Bulletin Immunology and Allergy, Vol: 2, Pages: 40-43
  6. Murray CS, et al. Am J Respir Crit Care Med 2017;196(2); 150-158
  7. Morgan WJ, et al. N Engl J Med 2004;351(11):1068-1080.
  8. Zethraeus N, et al. Italian Journal of Pediatrics 2010;36:61.
  9. Green M, et al. BMJ 2002;324:1?5.
  10. Murray CS, et al. Thorax 2006;61:376'382.
  11. Smith HE, et al. J Allergy Clin Immunol 2009;123:646-50.
  12. 12. Pawankar R (Ed) et al. White book on allergy, 2011; World Allergy Organisation UK.
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